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Therefore, we did not calculate the performance characteristics for dd-cf DNA to discriminate active rejection in the scenario of no clinical indication for biopsy.The premise for quantitative interpretation of this biomarker is that rejection entails injury, including increased cell death in the allograft, leading to increased dd-cf DNA released into the bloodstream.Data from several single-center studies suggest that dd-cf DNA levels in blood, measured as a fraction of the total cell-free DNA (cf DNA), can discriminate rejection from nonrejection in heart, lung, liver, and kidney allografts.Finding them is easy with our totally FREE Belgaum dating service.

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The active rejection subgroup contained a higher proportion of black and deceased donor organ recipients than the group without active rejection and the overall DART population.